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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA CD52 CCLE pan-cancer AAC -0.3 2e-06
mRNA VIMP CCLE pan-cancer AAC 0.22 2e-06
mRNA LPXN CCLE pan-cancer AAC -0.27 3e-06
mRNA CD28 CCLE pan-cancer AAC 0.23 3e-06
mRNA CASP10 CCLE pan-cancer AAC 0.23 3e-06
mRNA DUSP16 CCLE pan-cancer AAC 0.22 3e-06
mRNA CCHCR1 CCLE pan-cancer AAC -0.21 3e-06
mRNA TBC1D10C CCLE pan-cancer AAC -0.32 3e-06
mRNA SPIB CCLE pan-cancer AAC -0.25 3e-06
mRNA INSR CCLE pan-cancer AAC 0.23 3e-06
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