1. Home/
  2. Compounds/
  3. AEW541

AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA ZC3H12D CCLE pan-cancer AAC -0.3 9e-07
mRNA SNX18 CCLE pan-cancer AAC 0.22 1e-06
mRNA MYO1G CCLE pan-cancer AAC -0.35 1e-06
mRNA H1FX CCLE pan-cancer AAC 0.22 1e-06
mRNA DOLPP1 CCLE pan-cancer AAC 0.22 1e-06
mRNA BMP8B CCLE pan-cancer AAC 0.23 2e-06
mRNA DENND1C CCLE pan-cancer AAC -0.32 2e-06
mRNA IGF1 CCLE pan-cancer AAC 0.22 2e-06
mRNA GCSAM CCLE pan-cancer AAC -0.28 2e-06
mRNA BMP6 CCLE pan-cancer AAC 0.22 2e-06
Download CSV