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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA KLF3 CCLE pan-cancer AAC 0.25 4e-07
mRNA ARID3A CCLE pan-cancer AAC 0.26 5e-07
mRNA STAP1 CCLE pan-cancer AAC -0.31 5e-07
mRNA FAM63A CCLE pan-cancer AAC 0.23 5e-07
mRNA TLR10 CCLE pan-cancer AAC -0.26 6e-07
mRNA SIT1 CCLE pan-cancer AAC -0.27 8e-07
mRNA VNN2 CCLE pan-cancer AAC -0.25 8e-07
mRNA CD19 CCLE pan-cancer AAC -0.26 8e-07
mRNA AQP3 CCLE pan-cancer AAC 0.24 9e-07
mRNA KIAA0922 CCLE pan-cancer AAC -0.26 9e-07
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