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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA CDKL1 CCLE pan-cancer AAC -0.1 0.02
mRNA EIF2S1 CCLE pan-cancer AAC -0.11 0.02
mRNA HNRNPH2 CCLE pan-cancer AAC 0.1 0.02
mRNA SLC19A2 CCLE pan-cancer AAC 0.11 0.02
mRNA MAPK9 CCLE pan-cancer AAC -0.11 0.02
mRNA RAPH1 CCLE pan-cancer AAC 0.13 0.02
mRNA GMFG CCLE pan-cancer AAC 0.18 0.02
mRNA NPTN CCLE pan-cancer AAC 0.11 0.02
mRNA ASF1B CCLE pan-cancer AAC -0.11 0.02
mRNA MFSD2A CCLE pan-cancer AAC -0.1 0.02
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