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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA AMPD1 CCLE pan-cancer AAC 0.31 1e-11
mRNA IGF1R CCLE pan-cancer AAC 0.32 1e-11
mRNA TP53INP1 CCLE pan-cancer AAC 0.29 7e-10
mRNA GPRC5D CCLE pan-cancer AAC 0.28 7e-10
mRNA DEK CCLE pan-cancer AAC -0.27 1e-09
mRNA NLRC3 CCLE pan-cancer AAC -0.42 6e-09
mRNA PTPRC CCLE pan-cancer AAC -0.42 2e-08
mRNA SASH3 CCLE pan-cancer AAC -0.4 2e-08
mRNA SWT1 CCLE pan-cancer AAC 0.26 2e-08
mRNA C1orf56 CCLE pan-cancer AAC 0.26 3e-08
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