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AEW541

Synonyms

SourcesNames Used
CCLEAEW541
PharmacoGx AEW541

External IDs

DatabaseIdentifier
Smiles: C1CN(C1)CC2CC(C2)N3C=C(C4=C3N=CN=C4N)C5=CC(=CC=C5)OCC6=CC=CC=C6
Inchikey: AECDBHGVIIRMOI-UHFFFAOYSA-N
Pubchem: 11476171

Annotated Targets

IGF1R

FDA Approval Status

Not Approved
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Top molecular features associated with response to AEW541


Feature TypeStandardized
Nominal ANOVA
mRNA SLC44A2 CCLE pan-cancer AAC -0.11 0.02
mRNA CYTH3 CCLE pan-cancer AAC -0.12 0.02
mRNA HAVCR2 CCLE pan-cancer AAC -0.11 0.02
mRNA MEGF9 CCLE pan-cancer AAC 0.1 0.02
mRNA TMC8 CCLE pan-cancer AAC 0.16 0.02
mRNA HACD3 CCLE pan-cancer AAC 0.11 0.02
mRNA ASRGL1 CCLE pan-cancer AAC 0.11 0.02
mRNA TMCC3 CCLE pan-cancer AAC 0.11 0.02
mRNA DNASE1L3 CCLE pan-cancer AAC -0.11 0.02
mRNA KRTAP3-2 CCLE pan-cancer AAC 0.1 0.02
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