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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA TNFRSF17 CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA SASH3 CTRPv2 pan-cancer AAC -0.24 2e-07
mRNA MCUB CTRPv2 pan-cancer AAC -0.19 2e-07
mRNA TIFAB GDSC1000 pan-cancer AAC 0.16 2e-07
mRNA BMP8B GDSC1000 pan-cancer AAC 0.16 3e-07
mRNA PDE3B GDSC1000 pan-cancer AAC 0.18 3e-07
mRNA CCR2 GDSC1000 pan-cancer AAC 0.17 3e-07
mRNA CD22 CTRPv2 pan-cancer AAC -0.19 4e-07
mRNA C7orf77 CTRPv2 pan-cancer AAC 0.18 4e-07
mRNA FAM46C CTRPv2 pan-cancer AAC 0.19 4e-07
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