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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA CTSO CTRPv2 pan-cancer AAC 0.18 5e-07
mRNA INSR GDSC1000 pan-cancer AAC 0.17 5e-07
mRNA DTX1 CTRPv2 pan-cancer AAC -0.19 5e-07
mRNA NLRC3 CTRPv2 pan-cancer AAC -0.22 6e-07
mRNA CEP85L CTRPv2 pan-cancer AAC -0.19 6e-07
mRNA SIT1 GDSC1000 pan-cancer AAC -0.2 7e-07
mRNA INPP4A CTRPv2 pan-cancer AAC 0.18 8e-07
mRNA EDEM3 CTRPv2 pan-cancer AAC 0.18 8e-07
mRNA SLAMF6 CTRPv2 pan-cancer AAC -0.19 8e-07
mRNA CORO7-PAM16 CTRPv2 pan-cancer AAC 0.23 9e-07
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