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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA POLH CTRPv2 pan-cancer AAC -0.16 5e-05
mRNA GNA13 GDSC1000 pan-cancer AAC -0.14 5e-05
mRNA AC013264.1 CTRPv2 pan-cancer AAC -0.17 5e-05
mRNA OCSTAMP GDSC1000 pan-cancer AAC 0.13 5e-05
mRNA TESPA1 GDSC1000 pan-cancer AAC -0.18 5e-05
mRNA KLHL18 CTRPv2 pan-cancer AAC -0.15 5e-05
mRNA GOLGA8M CTRPv2 pan-cancer AAC 0.14 5e-05
mRNA HLTF CTRPv2 pan-cancer AAC -0.15 5e-05
mRNA SNAI3 CTRPv2 pan-cancer AAC 0.16 5e-05
mRNA CD37 CTRPv2 pan-cancer AAC -0.16 5e-05
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