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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA VWA7 CTRPv2 pan-cancer AAC 0.096 0.008
mRNA ABLIM3 GDSC1000 pan-cancer AAC -0.095 0.008
mRNA AC027682.1 CTRPv2 pan-cancer AAC -0.097 0.008
mRNA ARHGAP26 GDSC1000 pan-cancer AAC 0.085 0.008
mRNA SV2B GDSC1000 pan-cancer AAC 0.09 0.008
mRNA PRTN3 CTRPv2 pan-cancer AAC 0.094 0.008
mRNA UBQLN2 GDSC1000 pan-cancer AAC 0.085 0.008
mRNA ANKRD36 CTRPv2 pan-cancer AAC -0.097 0.008
mRNA NCKAP1L GDSC1000 pan-cancer AAC 0.14 0.008
mRNA IQCD GDSC1000 pan-cancer AAC -0.085 0.008
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