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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA PIGM GDSC1000 pan-cancer AAC 0.15 8e-06
mRNA WDFY4 CTRPv2 pan-cancer AAC -0.18 8e-06
mRNA TMEM105 CTRPv2 pan-cancer AAC 0.16 8e-06
mRNA AMPD1 GDSC1000 pan-cancer AAC 0.14 8e-06
mRNA BCL7A CTRPv2 pan-cancer AAC -0.17 8e-06
mRNA MS4A1 GDSC1000 pan-cancer AAC -0.16 9e-06
mRNA FRAT2 GDSC1000 pan-cancer AAC 0.16 9e-06
mRNA ITSN2 CTRPv2 pan-cancer AAC -0.18 9e-06
mRNA SBK2 CTRPv2 pan-cancer AAC 0.16 1e-05
mRNA SMYD4 CTRPv2 pan-cancer AAC -0.16 1e-05
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