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BMS-536924

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BMS-536924
PharmacoGx BMS-536924

External IDs

DatabaseIdentifier
Smiles: CC1=CC(=CC2=C1NC(=C3C(=CC=NC3=O)NCC(C4=CC(=CC=C4)Cl)O)N2)N5CCOCC5
Inchikey: UGQMURPIMYALPH-PZJQAWQVSA-N
Pubchem: 10390396

Annotated Targets

AKT1, CCNE1, CDK2, CYP3A4, ERBB2, IGF1R, KDR, LCK, MAPK1, MET, PDGFRA, PDGFRB, INSR

FDA Approval Status

Not Approved
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Top molecular features associated with response to BMS-536924


Feature TypeStandardized
Nominal ANOVA
mRNA BRD3 GDSC1000 pan-cancer AAC 0.089 0.008
mRNA TRIQK GDSC1000 pan-cancer AAC 0.092 0.008
mRNA JMY CTRPv2 pan-cancer AAC 0.094 0.008
mRNA EXOC6 GDSC1000 pan-cancer AAC 0.092 0.008
mRNA IFRD1 GDSC1000 pan-cancer AAC -0.085 0.008
mRNA NFKBID CTRPv2 pan-cancer AAC -0.096 0.008
mRNA POU2F1 CTRPv2 pan-cancer AAC -0.11 0.008
mRNA LSM10 GDSC1000 pan-cancer AAC -0.094 0.008
mRNA SLC22A2 CTRPv2 pan-cancer AAC 0.099 0.008
mRNA MKNK2 GDSC1000 pan-cancer AAC -0.085 0.008
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