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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA SUPT16H CTRPv2 pan-cancer AAC 0.2 5e-10
mRNA SNRPA CTRPv2 pan-cancer AAC 0.22 5e-10
mRNA PLK1 CTRPv2 pan-cancer AAC 0.19 5e-10
mRNA ANXA5 CTRPv2 pan-cancer AAC -0.26 6e-10
mRNA CHAF1A CTRPv2 pan-cancer AAC 0.22 6e-10
mRNA CCNF CTRPv2 pan-cancer AAC 0.2 6e-10
mRNA ZNF280C CTRPv2 pan-cancer AAC 0.2 6e-10
mRNA CD59 CTRPv2 pan-cancer AAC -0.22 6e-10
mRNA MLPH CTRPv2 pan-cancer AAC -0.21 7e-10
mRNA FAM98B CTRPv2 pan-cancer AAC 0.2 7e-10
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