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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA ANP32B CTRPv2 pan-cancer AAC 0.25 3e-12
mRNA HNRNPM CTRPv2 pan-cancer AAC 0.22 3e-12
mRNA MDN1 CTRPv2 pan-cancer AAC 0.24 3e-12
mRNA RHBDF1 CTRPv2 pan-cancer AAC -0.26 4e-12
mRNA BUB1B CTRPv2 pan-cancer AAC 0.23 4e-12
mRNA ELAVL1 CTRPv2 pan-cancer AAC 0.23 5e-12
mRNA SSRP1 CTRPv2 pan-cancer AAC 0.21 5e-12
mRNA CEP295NL CTRPv2 pan-cancer AAC -0.26 5e-12
mRNA ILF3 CTRPv2 pan-cancer AAC 0.24 6e-12
mRNA ARHGAP19-SLIT1 CTRPv2 pan-cancer AAC 0.26 6e-12
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