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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA PSMC3IP CTRPv2 pan-cancer AAC 0.12 0.0002
mRNA NEUROD1 CTRPv2 pan-cancer AAC 0.12 0.0002
mRNA SGK494 CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA FAM216A CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA TOMM5 CTRPv2 pan-cancer AAC 0.12 0.0002
mRNA PLK4 GDSC1000 pan-cancer AAC 0.22 0.0002
mRNA RNF2 CTRPv2 pan-cancer AAC 0.12 0.0002
mRNA TMUB2 CTRPv2 pan-cancer AAC -0.12 0.0002
mRNA ZBTB37 CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA RPS10-NUDT3 CTRPv2 pan-cancer AAC 0.13 0.0002
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