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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA COX7A1 CTRPv2 pan-cancer AAC -0.12 0.0001
mRNA CDAN1 CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA MSH5 CTRPv2 pan-cancer AAC 0.14 0.0002
mRNA LAMA3 CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA ICE1 GDSC1000 pan-cancer AAC 0.19 0.0002
mRNA RRP1 CTRPv2 pan-cancer AAC 0.12 0.0002
mRNA P4HA2 CTRPv2 pan-cancer AAC -0.13 0.0002
mRNA APPL1 CTRPv2 pan-cancer AAC 0.13 0.0002
mRNA KIAA0513 CTRPv2 pan-cancer AAC -0.12 0.0002
mRNA TACSTD2 CTRPv2 pan-cancer AAC -0.14 0.0002
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