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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA SRSF7 CTRPv2 pan-cancer AAC 0.23 5e-11
mRNA ATP6V0E1 CTRPv2 pan-cancer AAC -0.23 6e-11
mRNA RHOC CTRPv2 pan-cancer AAC -0.24 6e-11
mRNA BLM CTRPv2 pan-cancer AAC 0.25 6e-11
mRNA LRPPRC CTRPv2 pan-cancer AAC 0.21 6e-11
mRNA PFAS CTRPv2 pan-cancer AAC 0.22 6e-11
mRNA SMIM8 CTRPv2 pan-cancer AAC 0.22 7e-11
mRNA PTBP1 CTRPv2 pan-cancer AAC 0.21 7e-11
mRNA PELP1 CTRPv2 pan-cancer AAC 0.21 7e-11
mRNA CAD CTRPv2 pan-cancer AAC 0.22 7e-11
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