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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA TFAP4 CTRPv2 pan-cancer AAC 0.25 8e-13
mRNA CDCA7 CTRPv2 pan-cancer AAC 0.25 9e-13
mRNA KLHL23 CTRPv2 pan-cancer AAC 0.24 1e-12
mRNA SNRNP40 CTRPv2 pan-cancer AAC 0.23 1e-12
mRNA ZBED4 CTRPv2 pan-cancer AAC 0.26 1e-12
mRNA SMARCC1 CTRPv2 pan-cancer AAC 0.25 1e-12
mRNA WDR33 CTRPv2 pan-cancer AAC 0.23 2e-12
mRNA EPS8L2 CTRPv2 pan-cancer AAC -0.26 2e-12
mRNA CPSF6 CTRPv2 pan-cancer AAC 0.25 2e-12
mRNA RBM10 CTRPv2 pan-cancer AAC 0.24 2e-12
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