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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA SNRPF CTRPv2 pan-cancer AAC 0.22 6e-12
mRNA RUVBL1 CTRPv2 pan-cancer AAC 0.21 7e-12
mRNA NDUFAF4 CTRPv2 pan-cancer AAC 0.23 7e-12
mRNA HNRNPA0 CTRPv2 pan-cancer AAC 0.23 8e-12
mRNA RP11-426L16.10 CTRPv2 pan-cancer AAC -0.25 9e-12
mRNA CD151 CTRPv2 pan-cancer AAC -0.26 9e-12
mRNA NONO CTRPv2 pan-cancer AAC 0.22 1e-11
mRNA IRAK1BP1 CTRPv2 pan-cancer AAC 0.22 1e-11
mRNA EXOSC9 CTRPv2 pan-cancer AAC 0.23 1e-11
mRNA PEA15 CTRPv2 pan-cancer AAC -0.25 1e-11
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