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BI-2536

Synonyms

SourcesNames Used
GDSC1000, CTRPv2BI-2536
FIMMBI 2536
PharmacoGx BI-2536

External IDs

DatabaseIdentifier
Smiles: CCC1C(=O)N(C2=CN=C(N=C2N1C3CCCC3)NC4=C(C=C(C=C4)C(=O)NC5CCN(CC5)C)OC)C
Inchikey: XQVVPGYIWAGRNI-JOCHJYFZSA-N
Pubchem: 11364421

Annotated Targets

BRD4, PLK1, PLK2, PLK3

FDA Approval Status

Not Approved
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Top molecular features associated with response to BI-2536


Feature TypeStandardized
Nominal ANOVA
mRNA XRCC5 CTRPv2 pan-cancer AAC 0.18 8e-09
mRNA DDX39B CTRPv2 pan-cancer AAC 0.19 8e-09
mRNA GAS6 CTRPv2 pan-cancer AAC -0.18 9e-09
mRNA WASF1 CTRPv2 pan-cancer AAC 0.2 9e-09
mRNA TCERG1 CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA SMU1 CTRPv2 pan-cancer AAC 0.18 1e-08
mRNA PAPOLG CTRPv2 pan-cancer AAC 0.19 1e-08
mRNA BCLAF1 CTRPv2 pan-cancer AAC 0.18 1e-08
mRNA HNRNPK CTRPv2 pan-cancer AAC 0.18 1e-08
mRNA PPRC1 CTRPv2 pan-cancer AAC 0.19 1e-08
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