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AUY922

AUY922

Synonyms

Sources	Names Used
GDSC1000	AUY922
PharmacoGx	AUY922

External IDs

Database	Identifier
Smiles:	CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Inchikey:	SWDZPNJZKUGIIH-QQTULTPQSA-N
Pubchem:	10096043

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AUY922

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	GNG4	GDSC1000	pan-cancer	AAC	-0.2	3e-07
mRNA	KIF5C	GDSC1000	pan-cancer	AAC	-0.19	3e-07
mRNA	B3GNTL1	GDSC1000	pan-cancer	AAC	0.18	3e-07
mRNA	CBLN1	GDSC1000	pan-cancer	AAC	-0.18	3e-07
mRNA	SLC7A14	GDSC1000	pan-cancer	AAC	-0.19	4e-07
mRNA	STMN2	GDSC1000	pan-cancer	AAC	-0.22	4e-07
mRNA	IGF2BP2	GDSC1000	pan-cancer	AAC	0.21	4e-07
mRNA	SLC25A37	GDSC1000	pan-cancer	AAC	0.18	4e-07
mRNA	ATL1	GDSC1000	pan-cancer	AAC	-0.19	4e-07
mRNA	CYR61	GDSC1000	pan-cancer	AAC	0.24	4e-07

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