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AUY922

AUY922

Synonyms

Sources	Names Used
GDSC1000	AUY922
PharmacoGx	AUY922

External IDs

Database	Identifier
Smiles:	CCNC(=O)C1=C(C(=C2C=C(C(=CC2=O)O)C(C)C)ON1)C3=CC=C(C=C3)CN4CCOCC4
Inchikey:	SWDZPNJZKUGIIH-QQTULTPQSA-N
Pubchem:	10096043

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AUY922

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	NRCAM	GDSC1000	pan-cancer	AAC	-0.2	7e-09
mRNA	ELAVL3	GDSC1000	pan-cancer	AAC	-0.23	1e-08
mRNA	WDFY2	GDSC1000	pan-cancer	AAC	0.2	1e-08
mRNA	RGS10	GDSC1000	pan-cancer	AAC	0.2	1e-08
mRNA	TNFRSF1A	GDSC1000	pan-cancer	AAC	0.21	2e-08
mRNA	DSE	GDSC1000	pan-cancer	AAC	0.22	2e-08
mRNA	NRSN1	GDSC1000	pan-cancer	AAC	-0.22	2e-08
mRNA	PEX5L	GDSC1000	pan-cancer	AAC	-0.2	2e-08
mRNA	SCN3A	GDSC1000	pan-cancer	AAC	-0.19	3e-08
mRNA	ELK3	GDSC1000	pan-cancer	AAC	0.2	3e-08

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