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OSI-906

OSI-906

Synonyms

Sources	Names Used
CTRPv2	linsitinib
PharmacoGx	OSI-906

External IDs

Database	Identifier
Smiles:	CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Inchikey:	PKCDDUHJAFVJJB-UHFFFAOYSA-N
Pubchem:	11640390

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-906

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PIM2	CTRPv2	pan-cancer	AAC	0.27	1e-13
mRNA	MANEA	CTRPv2	pan-cancer	AAC	0.26	3e-13
mRNA	CD320	CTRPv2	pan-cancer	AAC	0.25	5e-13
mRNA	ATP8B2	CTRPv2	pan-cancer	AAC	0.26	8e-13
mRNA	TMCO1	CTRPv2	pan-cancer	AAC	0.25	8e-13
mRNA	IRF4	CTRPv2	pan-cancer	AAC	0.27	1e-12
mRNA	ARHGEF2	CTRPv2	pan-cancer	AAC	0.28	1e-12
mRNA	GPRIN3	CTRPv2	pan-cancer	AAC	0.24	1e-12
mRNA	PLEKHH3	CTRPv2	pan-cancer	AAC	0.24	2e-12
mRNA	SSR2	CTRPv2	pan-cancer	AAC	0.24	2e-12

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