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OSI-906

OSI-906

Synonyms

Sources	Names Used
CTRPv2	linsitinib
PharmacoGx	OSI-906

External IDs

Database	Identifier
Smiles:	CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Inchikey:	PKCDDUHJAFVJJB-UHFFFAOYSA-N
Pubchem:	11640390

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-906

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	METTL7A	CTRPv2	pan-cancer	AAC	0.21	2e-08
mRNA	SETBP1	CTRPv2	pan-cancer	AAC	0.2	2e-08
mRNA	DBX1	CTRPv2	pan-cancer	AAC	0.19	2e-08
mRNA	CLCNKA	CTRPv2	pan-cancer	AAC	0.19	2e-08
mRNA	CADPS2	CTRPv2	pan-cancer	AAC	0.2	2e-08
mRNA	MYOG	CTRPv2	pan-cancer	AAC	0.2	2e-08
mRNA	CTAG1B	CTRPv2	pan-cancer	AAC	0.19	2e-08
mRNA	ENPP6	CTRPv2	pan-cancer	AAC	0.19	2e-08
mRNA	GLB1L2	CTRPv2	pan-cancer	AAC	0.22	2e-08
mRNA	CTAG1A	CTRPv2	pan-cancer	AAC	0.19	2e-08

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