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OSI-906

OSI-906

Synonyms

Sources	Names Used
CTRPv2	linsitinib
PharmacoGx	OSI-906

External IDs

Database	Identifier
Smiles:	CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Inchikey:	PKCDDUHJAFVJJB-UHFFFAOYSA-N
Pubchem:	11640390

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to OSI-906

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ACP6	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	SPRR2B	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	SEZ6	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	NUB1	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	RAP2C	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	SH3BGRL2	CTRPv2	pan-cancer	AAC	0.13	0.002
mRNA	SLC43A3	CTRPv2	pan-cancer	AAC	-0.13	0.002
mRNA	CAPZB	CTRPv2	pan-cancer	AAC	-0.11	0.002
mRNA	MPND	CTRPv2	pan-cancer	AAC	0.11	0.002
mRNA	ACY1	CTRPv2	pan-cancer	AAC	0.12	0.002

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