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OSI-906

Synonyms

SourcesNames Used
CTRPv2linsitinib
PharmacoGx OSI-906

External IDs

DatabaseIdentifier
Smiles: CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Inchikey: PKCDDUHJAFVJJB-UHFFFAOYSA-N
Pubchem: 11640390

FDA Approval Status

Not Approved
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Top molecular features associated with response to OSI-906


Feature TypeStandardized
Nominal ANOVA
mRNA ARMC2 CTRPv2 pan-cancer AAC 0.3 5e-19
mRNA DERL3 CTRPv2 pan-cancer AAC 0.3 4e-18
mRNA PMVK CTRPv2 pan-cancer AAC 0.31 5e-18
mRNA ENAM CTRPv2 pan-cancer AAC 0.31 6e-18
mRNA AMPD1 CTRPv2 pan-cancer AAC 0.29 1e-17
mRNA MZB1 CTRPv2 pan-cancer AAC 0.33 3e-17
mRNA TXNDC11 CTRPv2 pan-cancer AAC 0.3 4e-17
mRNA SLC25A20 CTRPv2 pan-cancer AAC 0.31 4e-17
mRNA PRKAG3 CTRPv2 pan-cancer AAC 0.28 1e-16
mRNA C7orf77 CTRPv2 pan-cancer AAC 0.28 1e-16
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