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GSK-650394

Synonyms

SourcesNames Used
GDSC1000GSK-650394
GRAYGSK650394
PharmacoGx GSK-650394

External IDs

DatabaseIdentifier
Smiles: C1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=NC=C(C=C34)C5=CC=CC=C5)C(=O)O
Inchikey: WVSBGSNVCDAMCF-UHFFFAOYSA-N
Pubchem: 25022668

Annotated Targets

SGK1, SGK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to GSK-650394


Feature TypeStandardized
Nominal ANOVA
mRNA AP4E1 GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA NIFK GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA SIGLEC7 GDSC1000 pan-cancer AAC 0.14 0.0001
mRNA ORAI2 GDSC1000 pan-cancer AAC -0.16 0.0001
mRNA EIF2S2 GDSC1000 pan-cancer AAC 0.13 0.0001
mRNA ACBD3 GDSC1000 pan-cancer AAC -0.13 0.0001
mRNA FAM78B GDSC1000 pan-cancer AAC -0.15 0.0001
mRNA P2RX1 GDSC1000 pan-cancer AAC 0.16 0.0001
mRNA PPAT GDSC1000 pan-cancer AAC 0.15 0.0001
mRNA MAP4K1 GDSC1000 pan-cancer AAC -0.2 0.0001
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