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FTI-277

Synonyms

SourcesNames Used
GDSC1000FTI-277
PharmacoGx FTI-277

External IDs

DatabaseIdentifier
Smiles: COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey: GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem: 3005532

FDA Approval Status

Not Approved
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Top molecular features associated with response to FTI-277


Feature TypeStandardized
Nominal ANOVA
mRNA AXL GDSC1000 pan-cancer AAC 0.14 0.0006
mRNA YAP1 GDSC1000 pan-cancer AAC 0.17 0.0006
mRNA DCLRE1B GDSC1000 pan-cancer AAC -0.12 0.0006
mRNA RAD54L GDSC1000 pan-cancer AAC -0.12 0.0006
mRNA DERL1 GDSC1000 pan-cancer AAC 0.12 0.0006
mRNA POLN GDSC1000 pan-cancer AAC -0.12 0.0006
mRNA GFPT1 GDSC1000 pan-cancer AAC 0.13 0.0006
mRNA TMBIM1 GDSC1000 pan-cancer AAC 0.14 0.0006
mRNA PAIP1 GDSC1000 pan-cancer AAC -0.13 0.0006
mRNA PDLIM7 GDSC1000 pan-cancer AAC 0.12 0.0006
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