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FTI-277

FTI-277

Synonyms

Sources	Names Used
GDSC1000	FTI-277
PharmacoGx	FTI-277

External IDs

Database	Identifier
Smiles:	COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey:	GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem:	3005532

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FTI-277

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TNFRSF12A	GDSC1000	pan-cancer	AAC	0.26	9e-08
mRNA	ZFAND3	GDSC1000	pan-cancer	AAC	0.18	3e-07
mRNA	ITGA3	GDSC1000	pan-cancer	AAC	0.21	5e-07
mRNA	PHLDA1	GDSC1000	pan-cancer	AAC	0.21	7e-07
mRNA	ABLIM3	GDSC1000	pan-cancer	AAC	0.18	7e-07
mRNA	VEGFC	GDSC1000	pan-cancer	AAC	0.2	1e-06
mRNA	ATAD5	GDSC1000	pan-cancer	AAC	-0.18	1e-06
mRNA	C16orf72	GDSC1000	pan-cancer	AAC	0.16	1e-06
mRNA	GPC1	GDSC1000	pan-cancer	AAC	0.2	2e-06
mRNA	SERTAD1	GDSC1000	pan-cancer	AAC	0.17	3e-06

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