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FTI-277

Synonyms

SourcesNames Used
GDSC1000FTI-277
PharmacoGx FTI-277

External IDs

DatabaseIdentifier
Smiles: COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey: GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem: 3005532

FDA Approval Status

Not Approved
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Top molecular features associated with response to FTI-277


Feature TypeStandardized
Nominal ANOVA
mRNA SEC11C GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA NPC1 GDSC1000 pan-cancer AAC 0.13 0.0002
mRNA GNG4 GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA RND3 GDSC1000 pan-cancer AAC 0.16 0.0002
mRNA PLEC GDSC1000 pan-cancer AAC 0.14 0.0002
mRNA COBL GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA TSPAN4 GDSC1000 pan-cancer AAC 0.15 0.0002
mRNA GINS1 GDSC1000 pan-cancer AAC -0.12 0.0002
mRNA PAFAH1B3 GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA DCTD GDSC1000 pan-cancer AAC 0.13 0.0002
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