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FTI-277

Synonyms

SourcesNames Used
GDSC1000FTI-277
PharmacoGx FTI-277

External IDs

DatabaseIdentifier
Smiles: COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey: GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem: 3005532

FDA Approval Status

Not Approved
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Top molecular features associated with response to FTI-277


Feature TypeStandardized
Nominal ANOVA
mRNA MYB GDSC1000 pan-cancer AAC -0.18 0.0002
mRNA BDNF GDSC1000 pan-cancer AAC 0.14 0.0002
mRNA SYP GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA KDM3A GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA NUF2 GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA ELF2 GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA MAPT GDSC1000 pan-cancer AAC -0.14 0.0002
mRNA MED18 GDSC1000 pan-cancer AAC 0.14 0.0002
mRNA CDC45 GDSC1000 pan-cancer AAC -0.13 0.0002
mRNA IGSF9 GDSC1000 pan-cancer AAC -0.14 0.0002
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