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FTI-277

FTI-277

Synonyms

Sources	Names Used
GDSC1000	FTI-277
PharmacoGx	FTI-277

External IDs

Database	Identifier
Smiles:	COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey:	GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem:	3005532

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FTI-277

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DNMT3A	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	TADA1	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	ASPH	GDSC1000	pan-cancer	AAC	0.16	0.0001
mRNA	PRNP	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	MSRB3	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	TMEM167B	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	RASGEF1B	GDSC1000	pan-cancer	AAC	-0.13	0.0001
mRNA	ZBTB4	GDSC1000	pan-cancer	AAC	0.15	0.0001
mRNA	NASP	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	RFC3	GDSC1000	pan-cancer	AAC	-0.14	0.0001

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