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FTI-277

Synonyms

SourcesNames Used
GDSC1000FTI-277
PharmacoGx FTI-277

External IDs

DatabaseIdentifier
Smiles: COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey: GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem: 3005532

FDA Approval Status

Not Approved
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Top molecular features associated with response to FTI-277


Feature TypeStandardized
Nominal ANOVA
mRNA CARS GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA PPP1R18 GDSC1000 pan-cancer AAC 0.17 2e-05
mRNA PBRM1 GDSC1000 pan-cancer AAC -0.17 2e-05
mRNA LIF GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA GBE1 GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA GNA12 GDSC1000 pan-cancer AAC 0.15 2e-05
mRNA HBEGF GDSC1000 pan-cancer AAC 0.15 2e-05
mRNA HOOK1 GDSC1000 pan-cancer AAC -0.17 2e-05
mRNA TIMELESS GDSC1000 pan-cancer AAC -0.15 2e-05
mRNA PVR GDSC1000 pan-cancer AAC 0.16 2e-05
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