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FTI-277

FTI-277

Synonyms

Sources	Names Used
GDSC1000	FTI-277
PharmacoGx	FTI-277

External IDs

Database	Identifier
Smiles:	COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey:	GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem:	3005532

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FTI-277

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PLK3	GDSC1000	pan-cancer	AAC	0.13	0.0001
mRNA	HES6	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	TXNDC16	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	FLNA	GDSC1000	pan-cancer	AAC	0.14	0.0001
mRNA	BHLHB9	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	KIF15	GDSC1000	pan-cancer	AAC	-0.14	0.0001
mRNA	MCM4	GDSC1000	pan-cancer	AAC	-0.13	0.0002
mRNA	ZFPL1	GDSC1000	pan-cancer	AAC	0.13	0.0002
mRNA	FLOT1	GDSC1000	pan-cancer	AAC	0.14	0.0002
mRNA	SURF4	GDSC1000	pan-cancer	AAC	0.13	0.0002

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