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FTI-277

FTI-277

Synonyms

Sources	Names Used
GDSC1000	FTI-277
PharmacoGx	FTI-277

External IDs

Database	Identifier
Smiles:	COC(=O)C(CCSC)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2
Inchikey:	GKFPROVOIQKYTO-UZLBHIALSA-N
Pubchem:	3005532

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to FTI-277

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	FH	GDSC1000	pan-cancer	AAC	-0.081	0.02
mRNA	BRE	GDSC1000	pan-cancer	AAC	0.082	0.02
mRNA	MOGS	GDSC1000	pan-cancer	AAC	0.081	0.02
mRNA	ZNF407	GDSC1000	pan-cancer	AAC	-0.088	0.02
mRNA	TNRC6B	GDSC1000	pan-cancer	AAC	-0.089	0.02
mRNA	PLPP3	GDSC1000	pan-cancer	AAC	0.086	0.02
mRNA	TTC23L	GDSC1000	pan-cancer	AAC	0.08	0.02
mRNA	FEM1C	GDSC1000	pan-cancer	AAC	0.082	0.02
mRNA	PHRF1	GDSC1000	pan-cancer	AAC	-0.082	0.02
mRNA	PIEZO1	GDSC1000	pan-cancer	AAC	0.086	0.02

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