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AZD8055

AZD8055

Synonyms

Sources	Names Used
GDSC1000, CTRPv2	AZD8055
PharmacoGx	AZD8055

External IDs

Database	Identifier
Smiles:	CC1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOCC5C
Inchikey:	KVLFRAWTRWDEDF-IRXDYDNUSA-N
Pubchem:	25262965

Annotated Targets

FDA Approval Status

Not Approved

Dataset Select

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Top molecular features associated with response to AZD8055

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	DNAAF1	CTRPv2	pan-cancer	AAC	0.12	0.0007
mRNA	HSDL1	CTRPv2	pan-cancer	AAC	0.12	0.0007
mRNA	SLCO3A1	GDSC1000	pan-cancer	AAC	-0.12	0.0007
mRNA	LMCD1	CTRPv2	pan-cancer	AAC	-0.13	0.0007
mRNA	TMC4	CTRPv2	pan-cancer	AAC	-0.13	0.0007
mRNA	BTG2	CTRPv2	pan-cancer	AAC	0.13	0.0007
mRNA	ACAA2	CTRPv2	pan-cancer	AAC	0.13	0.0007
mRNA	EVI2B	GDSC1000	pan-cancer	AAC	0.17	0.0007
mRNA	FANCL	GDSC1000	pan-cancer	AAC	-0.12	0.0007
mRNA	PARP1	CTRPv2	pan-cancer	AAC	0.14	0.0007

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