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PD-0332991

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0332991
FIMMPalbociclib
PharmacoGx PD-0332991

External IDs

DatabaseIdentifier
Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
Inchikey: AHJRHEGDXFFMBM-UHFFFAOYSA-N
Pubchem: 5330286

FDA Approval Status

Approved
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Top molecular features associated with response to PD-0332991


Feature TypeStandardized
Nominal ANOVA
mRNA FAT1 GDSC1000 pan-cancer AAC 0.23 2e-07
mRNA LIMS2 GDSC1000 pan-cancer AAC 0.18 2e-07
mRNA FOSL1 GDSC1000 pan-cancer AAC 0.2 3e-07
mRNA C10orf76 GDSC1000 pan-cancer AAC 0.17 3e-07
mRNA PLIN3 GDSC1000 pan-cancer AAC 0.19 3e-07
mRNA RTN1 GDSC1000 pan-cancer AAC -0.2 3e-07
mRNA SLC2A8 GDSC1000 pan-cancer AAC -0.19 3e-07
mRNA CSNK2A2 GDSC1000 pan-cancer AAC 0.18 3e-07
mRNA SFXN3 GDSC1000 pan-cancer AAC 0.19 3e-07
mRNA PIP5K1B GDSC1000 pan-cancer AAC -0.2 3e-07
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