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PD-0332991

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0332991
FIMMPalbociclib
PharmacoGx PD-0332991

External IDs

DatabaseIdentifier
Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
Inchikey: AHJRHEGDXFFMBM-UHFFFAOYSA-N
Pubchem: 5330286

FDA Approval Status

Approved
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Top molecular features associated with response to PD-0332991


Feature TypeStandardized
Nominal ANOVA
mRNA EIF2S2 GDSC1000 pan-cancer AAC 0.096 0.004
mRNA ARL15 FIMM pan-cancer AAC 0.43 0.004
mRNA P2RX1 CCLE pan-cancer AAC 0.17 0.004
mRNA ATOX1 GDSC1000 pan-cancer AAC -0.11 0.004
mRNA ADAMTS15 CCLE pan-cancer AAC -0.14 0.004
mRNA RPL3 GDSC1000 pan-cancer AAC 0.11 0.004
mRNA NAA15 GDSC1000 pan-cancer AAC 0.1 0.004
mRNA PPFIBP2 CCLE pan-cancer AAC 0.14 0.004
mRNA PNMA1 CCLE pan-cancer AAC -0.15 0.004
mRNA IGFBP7 CCLE pan-cancer AAC -0.15 0.004
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