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PD-0332991

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0332991
FIMMPalbociclib
PharmacoGx PD-0332991

External IDs

DatabaseIdentifier
Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
Inchikey: AHJRHEGDXFFMBM-UHFFFAOYSA-N
Pubchem: 5330286

FDA Approval Status

Approved
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Top molecular features associated with response to PD-0332991


Feature TypeStandardized
Nominal ANOVA
mRNA CYB5A GDSC1000 pan-cancer AAC -0.19 1e-07
mRNA MLKL GDSC1000 pan-cancer AAC 0.19 1e-07
mRNA RUNX1 GDSC1000 pan-cancer AAC 0.19 1e-07
mRNA TTLL7 GDSC1000 pan-cancer AAC -0.19 1e-07
mRNA PRSS57 GDSC1000 pan-cancer AAC 0.19 1e-07
mRNA TSPAN12 GDSC1000 pan-cancer AAC -0.19 1e-07
mRNA INSM1 GDSC1000 pan-cancer AAC -0.2 2e-07
mRNA IMPDH2 GDSC1000 pan-cancer AAC 0.19 2e-07
mRNA TCEAL2 GDSC1000 pan-cancer AAC -0.18 2e-07
mRNA KARS GDSC1000 pan-cancer AAC 0.18 2e-07
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