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PD-0332991

Synonyms

SourcesNames Used
CCLE, GDSC1000PD-0332991
FIMMPalbociclib
PharmacoGx PD-0332991

External IDs

DatabaseIdentifier
Smiles: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C
Inchikey: AHJRHEGDXFFMBM-UHFFFAOYSA-N
Pubchem: 5330286

FDA Approval Status

Approved
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Top molecular features associated with response to PD-0332991


Feature TypeStandardized
Nominal ANOVA
mRNA DYNLT1 GDSC1000 pan-cancer AAC -0.19 2e-05
mRNA THAP4 GDSC1000 pan-cancer AAC 0.14 2e-05
mRNA STAT6 GDSC1000 pan-cancer AAC 0.17 2e-05
mRNA TMEM198 GDSC1000 pan-cancer AAC -0.16 2e-05
mRNA PTS CCLE pan-cancer AAC -0.23 2e-05
mRNA SVIL GDSC1000 pan-cancer AAC 0.17 2e-05
mRNA PTPN9 GDSC1000 pan-cancer AAC 0.15 2e-05
mRNA ASAP2 GDSC1000 pan-cancer AAC 0.22 2e-05
mRNA NICN1 GDSC1000 pan-cancer AAC 0.15 2e-05
mRNA UNC13C GDSC1000 pan-cancer AAC -0.15 2e-05
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