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MK-2206

Synonyms

SourcesNames Used
GDSC1000, CTRPv2MK-2206
PharmacoGx MK-2206

External IDs

DatabaseIdentifier
Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Inchikey: HWUHTJIKQZZBRA-UHFFFAOYSA-N
Pubchem: 46930998

Annotated Targets

AKT2, AKT1, AKT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to MK-2206


Feature TypeStandardized
Nominal ANOVA
mRNA GDF3 CTRPv2 pan-cancer AAC -0.098 0.005
mRNA C8orf88 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA RB1 GDSC1000 pan-cancer AAC 0.11 0.005
mRNA TNFAIP1 CTRPv2 pan-cancer AAC -0.11 0.005
mRNA H1FX CTRPv2 pan-cancer AAC 0.11 0.005
mRNA NEURL1B CTRPv2 pan-cancer AAC 0.1 0.005
mRNA PLEKHA3 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA SPRYD4 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA PPT2-EGFL8 CTRPv2 pan-cancer AAC -0.11 0.005
mRNA PSMD8 CTRPv2 pan-cancer AAC -0.1 0.005
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