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MK-2206

Synonyms

SourcesNames Used
GDSC1000, CTRPv2MK-2206
PharmacoGx MK-2206

External IDs

DatabaseIdentifier
Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Inchikey: HWUHTJIKQZZBRA-UHFFFAOYSA-N
Pubchem: 46930998

Annotated Targets

AKT2, AKT1, AKT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to MK-2206


Feature TypeStandardized
Nominal ANOVA
mRNA NDST3 GDSC1000 pan-cancer AAC 0.1 0.005
mRNA MBTD1 CTRPv2 pan-cancer AAC 0.12 0.005
mRNA ALAS1 CTRPv2 pan-cancer AAC -0.1 0.005
mRNA ZSCAN25 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA RCSD1 GDSC1000 pan-cancer AAC 0.18 0.005
mRNA TMEM216 GDSC1000 pan-cancer AAC -0.11 0.005
mRNA HNRNPH1 CTRPv2 pan-cancer AAC 0.11 0.005
mRNA ESAM CTRPv2 pan-cancer AAC -0.1 0.005
mRNA ADCYAP1R1 CTRPv2 pan-cancer AAC 0.17 0.005
mRNA PDLIM3 CTRPv2 pan-cancer AAC 0.1 0.005
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