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MK-2206

Synonyms

SourcesNames Used
GDSC1000, CTRPv2MK-2206
PharmacoGx MK-2206

External IDs

DatabaseIdentifier
Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Inchikey: HWUHTJIKQZZBRA-UHFFFAOYSA-N
Pubchem: 46930998

Annotated Targets

AKT2, AKT1, AKT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to MK-2206


Feature TypeStandardized
Nominal ANOVA
mRNA TCF3 CTRPv2 pan-cancer AAC 0.21 9e-07
mRNA TAB1 CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA RHOH CTRPv2 pan-cancer AAC 0.21 1e-06
mRNA CYFIP2 CTRPv2 pan-cancer AAC 0.21 1e-06
mRNA INSR CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA CKMT1A CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA TAL1 CTRPv2 pan-cancer AAC -0.17 1e-06
mRNA FLAD1 CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA NLRC3 GDSC1000 pan-cancer AAC 0.27 2e-06
mRNA EIF2AK3 CTRPv2 pan-cancer AAC 0.18 2e-06
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