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MK-2206

Synonyms

SourcesNames Used
GDSC1000, CTRPv2MK-2206
PharmacoGx MK-2206

External IDs

DatabaseIdentifier
Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Inchikey: HWUHTJIKQZZBRA-UHFFFAOYSA-N
Pubchem: 46930998

Annotated Targets

AKT2, AKT1, AKT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to MK-2206


Feature TypeStandardized
Nominal ANOVA
mRNA ARHGAP30 CTRPv2 pan-cancer AAC 0.28 7e-07
mRNA ITGAL CTRPv2 pan-cancer AAC 0.2 7e-07
mRNA CR1L CTRPv2 pan-cancer AAC -0.18 7e-07
mRNA ZNF407 CTRPv2 pan-cancer AAC 0.19 7e-07
mRNA CORO7-PAM16 CTRPv2 pan-cancer AAC 0.23 7e-07
mRNA STAM CTRPv2 pan-cancer AAC -0.18 7e-07
mRNA IFNLR1 CTRPv2 pan-cancer AAC 0.18 7e-07
mRNA SPG20 GDSC1000 pan-cancer AAC -0.21 8e-07
mRNA NCKAP1 GDSC1000 pan-cancer AAC -0.36 8e-07
mRNA BAK1 CTRPv2 pan-cancer AAC 0.18 9e-07
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