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MK-2206

Synonyms

SourcesNames Used
GDSC1000, CTRPv2MK-2206
PharmacoGx MK-2206

External IDs

DatabaseIdentifier
Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Inchikey: HWUHTJIKQZZBRA-UHFFFAOYSA-N
Pubchem: 46930998

Annotated Targets

AKT2, AKT1, AKT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to MK-2206


Feature TypeStandardized
Nominal ANOVA
mRNA CHIT1 CTRPv2 pan-cancer AAC 0.18 4e-07
mRNA HECA CTRPv2 pan-cancer AAC 0.2 4e-07
mRNA C17orf105 CTRPv2 pan-cancer AAC -0.18 5e-07
mRNA EAF2 CTRPv2 pan-cancer AAC 0.23 5e-07
mRNA CCDC78 CTRPv2 pan-cancer AAC 0.19 5e-07
mRNA STK17B CTRPv2 pan-cancer AAC 0.21 6e-07
mRNA PTK2B CTRPv2 pan-cancer AAC 0.23 6e-07
mRNA SGSM3 CTRPv2 pan-cancer AAC 0.19 6e-07
mRNA SPSB4 CTRPv2 pan-cancer AAC 0.2 7e-07
mRNA ANKRD46 CTRPv2 pan-cancer AAC 0.19 7e-07
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