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MK-2206

Synonyms

SourcesNames Used
GDSC1000, CTRPv2MK-2206
PharmacoGx MK-2206

External IDs

DatabaseIdentifier
Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Inchikey: HWUHTJIKQZZBRA-UHFFFAOYSA-N
Pubchem: 46930998

Annotated Targets

AKT2, AKT1, AKT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to MK-2206


Feature TypeStandardized
Nominal ANOVA
mRNA ITGB7 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA MFSD2B CTRPv2 pan-cancer AAC -0.16 4e-06
mRNA CREB3L4 CTRPv2 pan-cancer AAC 0.2 4e-06
mRNA GYPE CTRPv2 pan-cancer AAC -0.17 4e-06
mRNA AUTS2 CTRPv2 pan-cancer AAC 0.17 4e-06
mRNA HRASLS2 CTRPv2 pan-cancer AAC 0.16 4e-06
mRNA EDA CTRPv2 pan-cancer AAC 0.17 4e-06
mRNA PIAS4 CTRPv2 pan-cancer AAC 0.17 4e-06
mRNA CKMT1B CTRPv2 pan-cancer AAC 0.19 4e-06
mRNA CCNF CTRPv2 pan-cancer AAC 0.17 4e-06
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