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MK-2206

Synonyms

SourcesNames Used
GDSC1000, CTRPv2MK-2206
PharmacoGx MK-2206

External IDs

DatabaseIdentifier
Smiles: C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Inchikey: HWUHTJIKQZZBRA-UHFFFAOYSA-N
Pubchem: 46930998

Annotated Targets

AKT2, AKT1, AKT3

FDA Approval Status

Not Approved
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Top molecular features associated with response to MK-2206


Feature TypeStandardized
Nominal ANOVA
mRNA CD209 GDSC1000 pan-cancer AAC 0.1 0.005
mRNA ATP5J2 CTRPv2 pan-cancer AAC 0.099 0.005
mRNA MYC CTRPv2 pan-cancer AAC 0.11 0.005
mRNA IMMP2L GDSC1000 pan-cancer AAC -0.11 0.005
mRNA C1QTNF7 CTRPv2 pan-cancer AAC 0.097 0.005
mRNA TTLL1 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA BMP2K CTRPv2 pan-cancer AAC -0.11 0.005
mRNA MCHR1 CTRPv2 pan-cancer AAC 0.1 0.005
mRNA CD99 CTRPv2 pan-cancer AAC -0.11 0.005
mRNA CD33 CTRPv2 pan-cancer AAC -0.11 0.005
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