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ZM-447439

Synonyms

SourcesNames Used
GDSC1000ZM-447439
GRAYZM447439
PharmacoGx ZM-447439

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
Inchikey: OGNYUTNQZVRGMN-UHFFFAOYSA-N
Pubchem: 9914412

Annotated Targets

AURKA, AURKB

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZM-447439


Feature TypeStandardized
Nominal ANOVA
mRNA RHPN1 GDSC1000 pan-cancer AAC 0.17 2e-05
mRNA RRP7A GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA KDM1A GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA ABCB1 GDSC1000 pan-cancer AAC -0.17 2e-05
mRNA KDM4A GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA ERLIN1 GDSC1000 pan-cancer AAC 0.16 2e-05
mRNA SLC2A8 GDSC1000 pan-cancer AAC -0.17 2e-05
mRNA RNASEH2B GDSC1000 pan-cancer AAC 0.2 2e-05
mRNA MDFIC GDSC1000 pan-cancer AAC -0.16 2e-05
mRNA NUP43 GDSC1000 pan-cancer AAC 0.16 2e-05
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