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ZM-447439

Synonyms

SourcesNames Used
GDSC1000ZM-447439
GRAYZM447439
PharmacoGx ZM-447439

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
Inchikey: OGNYUTNQZVRGMN-UHFFFAOYSA-N
Pubchem: 9914412

Annotated Targets

AURKA, AURKB

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZM-447439


Feature TypeStandardized
Nominal ANOVA
mRNA ASIC1 GDSC1000 pan-cancer AAC 0.096 0.009
mRNA MED29 GDSC1000 pan-cancer AAC -0.094 0.009
mRNA ZC2HC1C GDSC1000 pan-cancer AAC -0.1 0.009
mRNA CREBL2 GDSC1000 pan-cancer AAC -0.1 0.009
mRNA THOC2 GDSC1000 pan-cancer AAC 0.099 0.009
mRNA MAP3K10 GDSC1000 pan-cancer AAC -0.093 0.009
mRNA TYRP1 GDSC1000 pan-cancer AAC -0.11 0.009
mRNA VARS GDSC1000 pan-cancer AAC 0.097 0.009
mRNA CLEC12A GDSC1000 pan-cancer AAC 0.095 0.009
mRNA E2F3 GDSC1000 pan-cancer AAC 0.1 0.009
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