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ZM-447439

Synonyms

SourcesNames Used
GDSC1000ZM-447439
GRAYZM447439
PharmacoGx ZM-447439

External IDs

DatabaseIdentifier
Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
Inchikey: OGNYUTNQZVRGMN-UHFFFAOYSA-N
Pubchem: 9914412

Annotated Targets

AURKA, AURKB

FDA Approval Status

Not Approved
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Top molecular features associated with response to ZM-447439


Feature TypeStandardized
Nominal ANOVA
mRNA GPATCH8 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA FASTKD1 GDSC1000 pan-cancer AAC 0.12 0.003
mRNA NOP16 GDSC1000 pan-cancer AAC 0.11 0.003
mRNA COPG1 GDSC1000 pan-cancer AAC -0.11 0.003
mRNA MANBAL GDSC1000 pan-cancer AAC -0.17 0.003
mRNA DEPTOR GDSC1000 pan-cancer AAC -0.11 0.003
mRNA DCP2 GDSC1000 pan-cancer AAC 0.13 0.003
mRNA FUCA2 GDSC1000 pan-cancer AAC -0.13 0.003
mRNA RNF157 GDSC1000 pan-cancer AAC -0.11 0.003
mRNA WDR12 GDSC1000 pan-cancer AAC 0.12 0.003
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